Table 5.
The table represents the factors which show over-representation in ChIP-seq MyoD-bound myoblast or myotube sequences (27)
| TRANSFAC IDs | Names | No. of promoters with z-score |
z-score | |
|---|---|---|---|---|
| Myoblast | Myotubes | |||
| M00174 | AP-1 | 376 (70.20) | 290 (51.77) | 7.70 |
| M01267 | FRA1 | 379 (72.46) | 298 (53.34) | 7.33 |
| M01034 | Ebox | 497 (5.08) | ||
| M01207 | ETS2 | 301 (57.97) | 327 (54.22) | 0.56 |
| M01281 | NFAT1 | 336 (24.96) | 367 (24.30) | 0.49 |
| M01266 | ELF1 | 710 (54.50) | 788 (57.71) | 0.26 |
| M01034 | Ebox | 497 (5.08) | ||
| M00805 | LEF1 | 303 (23.40) | 347 (24.92) | −0.41 |
| M00751 | AML1 | 572 (45.26) | 652 (55.20) | −0.44 |
| M00971 | Ets | 252 (38.12) | 294 (40.83) | −0.69 |
| M00658 | PU.1 | 273 (34.52) | 319 (48.88) | −0.74 |
| M01032 | HNF4 | 267 (19.97) | 313 (23.74) | −0.79 |
| M01488 | Meis2 | 370 (21.56) | 442 (23.84) | −1.31 |
| M00704 | TEF-1 | 358 (22.47) | 437 (31.18) | −1.72 |
| M01395 | MRG2 | 316 (20.59) | 388 (25.25) | −1.73 |
| M00277 | Lmo2 | 601 (12.84) | 724 (15.37) | −1.89 |
| M00070 | Tal-1beta:ITF-2 | 351 (11.58) | 439 (18.67) | −2.19 |
| M00065 | Tal-1beta:E47 | 304 (7.44) | 390 (11.00) | −2.51 |
| M01230 | ZNF333 | 326 (3.08) | 417 (8.34) | −2.54 |
| M01459 | PREP1 | 346 (18.78) | 441 (27.28) | −2.55 |
| M00419 | MEIS1 | 316 (20.79) | 412 (30.95) | −2.86 |
| M00066 | Tal-1alpha:E47 | 377 (9.69) | 487 (13.29) | −2.93 |
| M01411 | PKNOX2 | 447 (25.08) | 572 (32.94) | −2.98 |
| M01346 | TGIF1 | 371 (26.87) | 482 (34.22) | −3.03 |
| M00414 | AREB6 | 286 (8.00) | 391 (12.10) | −3.57 |
| M01160 | Kid3 | 1428 (19.87) | 1750 (30.50) | −3.60 |
| M00698 | HEB | 590 (38.93) | 762 (50.72) | −3.67 |
| M01139 | LMAF | 233 (34.82) | 328 (47.04) | −3.70 |
| M00974 | SMAD | 221 (26.68) | 320 (46.52) | −4.05 |
| M00993 | TAL1 | 767 (14.44) | 1004 (26.42) | −4.57 |
| M00644 | LBP-1 | 1170 (89.50) | 1488 (116.45) | −4.60 |
| M00071 | E47 | 561 (17.99) | 756 (27.68) | −4.64 |
| M00712 | myogenin | 1331 (31.05) | 1683 (48.57) | −4.69 |
| M00176 | AP-4 | 631 (42.93) | 855 (63.26) | −5.07 |
| M01227 | MAFB | 442 (24.17) | 628 (37.19) | −5.30 |
| M01288 | NeuroD | 1037 (74.42) | 1380 (105.26) | −5.88 |
| M00693 | E12 | 907 (8.04) | 1222 (18.56) | −5.90 |
| M00973 | E2A | 1087 (5.87) | 1446 (17.51) | −6.01 |
The factors having high number of occurrence in myoblasts and myotubes are selected in this table. The z-score is calculated for the occurrence of these selected factors with MyoD in myoblasts versus myotubes.