Figure 6.
Essential gene processes in V. cholerae. (A) V. cholerae genes predicted to be essential based on HMM analysis were categorized by their GO terms into broader biological processes to highlight essential activities in V. cholerae. (B) Essential hypothetical proteins from (A) were subjected to homology searches and protein fold threading to evaluate if additional functional assignments could be made for these genes. These analyses allowed preliminary categorization of the biological roles for 32 of the 46 essential hypothetical proteins into general biological categories.