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. 2013 Jul 16;5(9):1322–1334. doi: 10.1002/emmm.201302507

Figure 3. miR-373 promotes ZIP4-mediated pancreatic cancer cell invasion and proliferation.

Figure 3

  1. Relative cell invasion in AsPC-shV and AsPC-shZIP4 cells transfected with precursor miR-373 (Pre miR-373) and precursor control miRNA (Pre Ctrl) (significant p-value = 0.012, t-test, n = 3).
  2. Cell invasion in MIA-V and MIA-ZIP4 cells transfected with antisense miR-373 (Anti miR-373) and control (Anti Ctrl) oligos (significant p-value = 0.034, t-test, n = 3).
  3. Cell proliferation in miR-373 blocking MIA-ZIP4 cells. Cell proliferation was assessed by MTT assay and compared with day 0 value (p < 0.0001, t-test, n = 3).
  4. Wound healing assay. A representative view of wound healing was captured and recorded at 0 and 24 h. The scale bar in the image is 500 µm (p < 0.0001, t-test, n = 8). All data are mean ± SE.