Figure 1. The expression of miR-382 in the nucleus accumbens (NAc) of rats after treatment with alcohol: 18 male rats were treated with vehicle (500 µl saline, i.p. bid) or alcohol (1 g/kg, i.p. bid).

Seven days later, the animals were sacrificed and their NAc were isolated for miRNA microarray analysis, and miR-382 measurement by qRT-PCR. ***Student's t-test p < 0.0001, compared with that in vehicle-treated controls. Values are mean ± SEM from nine rats.

1. miR-382 was decreased in alcohol-treated rats as determined by microarray analysis. n = 9, p = 1.93E-10.
2. miR-382 was decreased in alcohol-treated rats as determined by qRT-PCR. n = 9, p = 6.53E-9.