Figure 2.

Treatments for lowering IOP. IOP is generated and maintained by the aqueous humour circulation system in the anterior eye. Aqueous humour is actively secreted by the ciliary body and is drained from the eye through the TM and the uveoscleral pathways. Conventional drugs as well as siRNA-based treatments for lowering IOP, by decreasing aqueous humour inflow and/or increasing aqueous humour outflow are indicated on the figure (modified from http://www.mdeyedocs.com/edcacuteglaucoma.htm).