Table 3.
Effects of treatment with RES on bone geometric and microstructural parameters of SCI rats
| Sham | Sham + RES | SCI | SCI + RES | |
|---|---|---|---|---|
| Tibia | ||||
| BMC (g) | 0.552 ± 0.058 | 0.591 ± 0.062 | 0.428 ± 0.051a | 0.535 ± 0.057b |
| BMD (g·cm−2) | 0.195 ± 0.022 | 0.204 ± 0.029 | 0.151 ± 0.018a | 0.182 ± 0.025b |
| BV/TV (%) | 16.3 ± 3.1 | 17.0 ± 3.6 | 7.9 ± 2.2a | 12.5 ± 2.8b |
| Tb.Th (μm) | 80.3 ± 11.5 | 82.1 ± 12.7 | 56.2 ± 8.8a | 72.2 ± 10.2b |
| Tb.Sp (μm) | 562.7 ± 80.3 | 574.2 ± 86.2 | 962.1 ± 102.5a | 660.5 ± 90.4b |
| Tb.N (n·mm−1) | 4.2 ± 1.4 | 4.3 ± 0.9 | 2.3 ± 0.7a | 3.5 ± 0.8b |
| MAR (μm·day−1) | 1.71 ± 0.19 | 1.79 ± 0.17 | 1.28 ± 0.20a | 1.66 ± 0.26b |
| BFR/BS (μm3·μm−2·day−1) | 0.57 ± 0.07 | 0.60 ± 0.06 | 0.40 ± 0.08a | 0.54 ± 0.09b |
| ES/BS (%) | 6.29 ± 0.65 | 6.01 ± 0.53 | 12.88 ± 1.32a | 8.55 ± 0.90b |
| Ob.S/BS (%) | 3.56 ± 0.34 | 3.69 ± 0.37 | 1.88 ± 0.21a | 3.20 ± 0.37b |
| Oc.S/BS (%) | 2.82 ± 0.45 | 2.75 ± 0.41 | 7.06 ± 0.94a | 4.24 ± 0.66b |
| Femur | ||||
| Ultimate load (N) | 209 ± 47 | 214 ± 42 | 141 ± 30a | 182 ± 39b |
| Stiffness (N·mm−1) | 480 ± 96 | 491 ± 81 | 358 ± 74a | 457 ± 85b |
| Energy (mJ) | 78 ± 16 | 80 ± 14 | 50 ± 13a | 67 ± 15b |
Values are represented as mean ± SD.
Sham, sham-operated.
n = 10–12 in each group.
a
P < 0.05 versus the sham-operated group.
b
P < 0.05 versus the SCI group.