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. 2013 Oct 18;8(10):e77228. doi: 10.1371/journal.pone.0077228

Figure 2. PTP1B deletion improves diet-induced insulin resistance and glucose uptake in skeletal muscle in mice.

Figure 2

(a) [3H]-2-deoxy-glucose-uptake assay (n = 6); (b) representative Western blots and (c) densitometric analysis (n = 6) of Akt phosphorylation in gastrocnemius muscles of the C57 or PTP1BKO mice received normal (ND) or high-fat content (HFD) diets for 20 weeks and challenged with insulin for 30 minutes. * p<0.05 compared with C57 ND mice, p<0.05 compared with C57 HFD mice.