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. 2013 Oct 18;8(10):e77177. doi: 10.1371/journal.pone.0077177

Figure 4. Asthma is an important risk factor for NK cell dysfunction in CRS and for CRS exacerbation.

Figure 4

The patients with CRS were classified into the asthma (+) and asthma (−) groups based on the diagnosis of clinical symptoms of asthma. (A) PBLs from normal controls (N, n = 19), the asthma (+) patients (n = 7) and the asthma (−) patients (n = 11) were stimulated and analyzed, as described in Figure 2. The three groups were compared in terms of CD107a, IFN-γ or TNF-α expression on NK cells. (B) Summary graphs of statistical dot plots showing the MFI of the indicated receptor expression on NK cells between the groups. *P<0.05; **P<0.005; ***P<0.001.