| Very Greatly | Greatly | Some | Little/No | Don’t know | ||
| 11. | Taking the risk of side effects (possible toxicity) involved with the treatment | — | — | — | — | — |
| 12. | The possibility of receiving a “placebo” or no treatment | — | — | — | — | — |
| 13. | Additional laboratory and/or x-ray tests required initially for eligibility | — | — | — | — | — |
| 14. | Additional testing or procedures required throughout treatment | — | — | — | — | — |
| 15. | The possibility of being randomized or assigned to a treatment by chance (like flipping a coin) | — | — | — | — | — |
| 16. | Feeling like I would be treated as a guinea pig | — | — | — | — | — |
| 17. | Concerns that the instructions for participation will be too complex | — | — | — | — | — |
| 18. | Concerns about insurance coverage | — | — | — | — | — |
| 19. | Demands too much of my personal time | — | — | — | — | — |
| 20. | Demands too much from my family members | — | — | — | — | — |
| 21. | Concerns about travel distance or transportation | — | — | — | — | — |
| 22. | Concerns about child care issues | — | — | — | — | — |
| 23. | Difficulty taking time off from work | — | — | — | — | — |