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. 2013 Oct 18;8(10):e76521. doi: 10.1371/journal.pone.0076521

Table 1. Fold-change in MIC/population/week (median of 3 tests/combination), relative to ancestral population.

Week
Treatment Population 1 2 3 4
Iseganan 1 8 >8 4 >16
2 8 >8 4 >16
3 8 8 ** >16
4 8 8 4 >16
5 8 8 4 >16
Melittin 1 4 4 8 32
2 2 2 8 4
3 2 4 8 4
4 2 2 16 16
5 2 16 16 16
Pexiganan 1 8 8 l l
2 8 8 l l
3 8 4 l l
4 4 8 l l
5 8 4 l l
Pexiganan & melittin 50∶50 1 2 1 e e
2 2 ** e e
3 4 4 e e
4 2 4 e e
5 4 2 e e
Vancomycin 1 >64 32 e e
2 >64 >64 e e
3 >64 8 e e
4 >64 32 e e
5 >64 32 e e
Streptomycin 1 >8 >8 >16 >16
2 >8 >8 >16 >16
3 >8 >8 >16 >16
4 >8 >8 >16 >16
5 >8 >8 >16 >16

Zero observed inhibition is denoted by indication of MIC greater than the fold-change in MIC that would be inferred by MIC at the greatest concentration of stressor assayed.

**

data excluded due to low OD upon inoculation into MIC assays.

l: low-density (pexiganan) and e: extinct cultures.