Table 1.

Characteristics of the study group.

	Hypertension (n=25)			No Hypertension (n=52)
	Baseline	Follow-up	Rate of change	Baseline	Follow-up	Rate of change
Age (year)	68.5±8.0^*			61.0± 9.2
Gender (%female)	52%			63%
Education (years)	17.2±2.0			16.7±2.2
ApoE4 carriers	17%			37%
Time between evaluations (years)	2.0± .50			1.9± .45
Mean arterial pressure (mmHg)	97.0±12.0^*	92.6±11.5^*	−2.1±8.3	87.3± 9.8	86.6± 9.1	−.47±7.2
Aβ42 (pg/mL)^a	596.6± 41.1	627.2±41.9	11.8±14.4	549.4±27.8	554.0±28.3	8.1±10.0
t-tau (pg/mL)^a	264.6±27.2	285.0±26.2	9.9± 7.7	290.0±18.4	301.4±17.7	4.9±5.3
p-tau₁₈₁(pg/mL )^a	48.5± 3.2	50.2±3.4	1.2± .80	47.6± 2.2	50.4±2.3	1.1± .60
Average fHipV (% of ICV)^b	.30±.006	.29±.005	−.002±.001	.29±.004	.28±.004	−.000±.000
MMSE	29.7±.56	29.2±1.5		29.1±1.3	29.2±1.1
Episodic verbal memory	.21±.71	.37±.92	.10±.38	−.10±.79	.04±.90	.09±.37
Framingham Cardiovascular Risk Profile^c	8.6± .80^*			6.1±.55
Hypercholesterolemia (%)	56%			60%
Diabetes (%)	4%			0%
Smoking (%)	0%			11%
BMI	28.8±6.6^*			25.3±3.6

The results are given as mean ± standard error after accounting for age. No covariates were necessary for the rates of change.

The results are given as mean ± standard error after accounting for age and gender. No covariates were necessary for atrophy rates.

The results are given as mean ± standard error after accounting for age and gender.

For the remaining variables, the values are presented as mean ± standard deviation.

Significant at p<.05, comparisons between HTN+ and HTN− groups

Rates of change are presented as unit per year

Memory measures are presented as z-scores

Framingham Cardiovascular Risk Profile represents % risk of coronary heart disease in the next 10 years

The results for hippocampal volume are presented for 73 subjects (25 HTN+ and 48 HTN−) BMI-Body Mass Index