Fig. 7.

Intra- and inter-molecular interactions detected by NMR are consistent with the EM model for the compact form of talin1. ¹⁵N-labeled talin1 double domains; F0F1, F2F3, R1–R2, R3–R4, R5–R6, R7–R8, R9–R10, R11–R12 and R13–DD were screened against 5 large unlabeled talin1 polypeptides F0–F3, R1–R3, R4–R8, R9–R12 and R13–DD. The proximity of the interacting fragments is illustrated by highlighting the fragments on the model. Bar represents 5 nm.