Figure 5. EPAS1 potentiates acute experimental colitis.
(A) Body weight, (B) colon length, (C) histological scoring, and (D) H&E staining of colon tissue after C. rod treatment for 7 days, 3% DSS for 5 days or regular water (Control) in Epas1LSL/+ (n=8) or littermate control mice (WT) (n=9) mice. Each bar or time point represents the mean value ± S.D.*p<0.05, **p<0.01 and ***p<0.001, compared to WT mice.