Pedigree and electropherogram of the family studied. A, Pedigree with autosomal recessive retinal degeneration segregates with the c.1381 C>T CDHR1 mutation. Squares indicate males; circles, females; shaded symbols, retinal degeneration; double lines, consanguinity; and slash marks, individuals who had died. B, Electropherograms with the sequence of the CDHR1 gene encompassing the c.1381 C/T region showing the homozygous c.1381 C>T change identified in the affected siblings, the sequence of an unaffected family member with the c.1381 C>T change in the heterozygous state, and the wild-type sequence at the c.1381 nucleotide of the CDHR1 gene.