Table 2.
MtDNAcn (MT/S) in controls, low and high exposed cokeoven workers: comparison of high-exposed workers with controls, and trend across PAH exposure categories
| Controls | Coke oven workers | |||||
|---|---|---|---|---|---|---|
|
n= 44 |
low exposure (1-pyrenol≤3)a n =24 |
high exposure (1-pyrenol>3)a n=22 |
p-value (high exposure vs. controls) |
p-value (high exposure vs. low exposure) |
p-value (Test for trend) |
|
| mtDNAcn (MT/S) geometric mean (95% CI) | 0.89 (0.81–0.98) | 0.91 (0.81–1.03) | 1.06 (0.93–1.18) | 0.029 | 0.08 | 0.043 |
| mtDNAcn (MT/S) Geometric mean (95% CI), age-adjusted | 0.89 (0,82–0.97) | 0.90 (0.80–1.01) | 1.07 (0.95–1.21) | 0.016 | 0.06 | 0.032 |
a
Coke-oven worked were divided in low and high exposure groups using the median levels of urinary 1-pyrenol, taken as a measure of exposure to PAHs