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. 2013 Oct 18;8(10):e76882. doi: 10.1371/journal.pone.0076882

Table 1. TRD and Non-TRD episode characteristics.

TRD patient characteristics TRD Episodes Non-TRD Episodes p-value
N 3,134 44,520
Number of patients 3,095 37,255
Female, N (%) 2,237 (72.3%) 25,733 (69.3%) <0.001
18–35 years, N (%) 927 (30.0%) 11,397 (30.6%) 0.46
36–50 years, N (%) 1,320 (42.6%) 15,087 (40.5%) 0.02
51–64 years, N (%) 848 (27.4%) 10,771 (28.9%) 0.07
Median Duration 891 298 <0.001
Mean Duration 1,004 452 <0.001
% TRD episodesa 6.6%
% TRD prevalenceb (i.e. %TRD episodes, adjusted for duration) 13.6%
Number of days to become TRD, mean [median], (quartile range) 479, [372],(214–640) NA
% of episodes that took more than 360 days to become TRD 52% NA
a

% TRD episodes are an approximation of TRD incidence.

b

TRD prevalence = TRD episode-days/(TRD episode days+non-TRD episode days)x100, where episode days are calculated as the number of episodes multiplied by mean duration.