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. 2013 Oct 18;8(10):e76882. doi: 10.1371/journal.pone.0076882

Table 3. Use of antidepressant classes as a % of episode duration.

Antidepressant Classes TRD episodes Non-TRD episodes (with at leastone ADAP prescription) P
Ho: MT = MN; H1: MT<>MN
SSRI 62% 70% a<0.001
ATYPICAL AD 24% 16% <0.001
SNRI 25% 15% <0.001
AD - OTHERS 24% 8% <0.001
AP 7% 2% <0.001
LITHIUM 0.4% 0.0% <0.001
AD – MAOI 0% 0% <0.001

Abbreviations: p = p-value, H0 = Null Hypothesis, H1 = Alternative Hypothesis; MT: The proportion of usage of an antidepressant in TRD episodes; MN: The proportion of usage of an antidepressant in non-TRD episodes; ADAP: Antidepressant and antipsychotic/antimanic drugs; SSRI: Selective serotonin reuptake inhibitor; SNRI: Serotonin Norepinephrine reuptake inhibitors; AD: Antidepressant; AP: Antipsychotics; MAOI: Monoamine oxidase inhibitors;

a

H1: MT<> MN.