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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Clin Cancer Res. 2013 Jul 15;19(17):4651–4661. doi: 10.1158/1078-0432.CCR-12-3630

Fig. 5. Influence of lamin B1 expression on pancreatic cancer growth in vivo.

Fig. 5

A. AsPC-1 and PANC-1 cells with lamin B1 knockdwon were injected subcutaneously (1×106 per mouse) into the right scapular region of nude mice. The tumor-bearing mice were sacrificed when they became moribund or on day 28. Shown were gross tumors in the mice. The tumors removed from the mice were weighed (*P<0.05 in a comparison between siLMNB1-transfected tumors and the parental or siCtrl ones): AsPC-1 (left panel) and PANC-1 (right panel). B. Knockdown of lamin B1 expression was observed in the xenograft tissues as determined by immunohistochemistry: AsPC-1 (left panel) and PANC-1 (right panel).