Fig. 3.
Antitumor activities of free and nanoparticle formulations of ODNs. a Effect of ODN therapy on growth of K562 xenograft tumors in nude mice. Tf-LP or free G3139 (5 mg/kg) was administered i.v. every other day starting on day 7 for a total of seven treatments. Tumor volume was monitored and plotted. b Effect of ODN therapy on survival of tumor-bearing nude mice. Nude mice (n=5) were untreated or injected i.v. with Tf-LP G4126, free G3139, or Tf-LP G3139.