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. Author manuscript; available in PMC: 2013 Oct 19.
Published in final edited form as: Epilepsia. 2011 Jan 4;52(3):551–561. doi: 10.1111/j.1528-1167.2010.02920.x

Figure 5. LAU-0901 attenuates hippocampal epileptiform electrical activity after SE.

Figure 5

(A) LAU-0901 shows no statistical difference for the percentage of spontaneous epileptic events in rats during the first three weeks after SE and (B) an increase in spontaneous seizures (stage 4-5) after SE (p > 0.07). (C) Representative hippocampal spontaneous electrical activity five weeks after SE from vehicle- and LAU-0901-treated rats. Epileptiform activity, represented by repetitive spikes or burst of spikes with high frequency components (underlines), are increased in vehicle-treated rats compared with LAU-0901. (D) LAU-0901-treated rats present fewer spontaneous numbers of spikes in the hippocampus after five weeks of SE, compared with vehicle-treated rats.