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. Author manuscript; available in PMC: 2014 Sep 21.
Published in final edited form as: Analyst. 2013 Jul 24;138(18):5384–5395. doi: 10.1039/c3an01174g

Figure 2.

Figure 2

On-chip sample formulation. (a) Optical micrograph of a chip filled with solutions of food coloring to illustrate the composition of samples formulated on-chip. Blue color represents lipid; green, concentrated detergent solution; red, diluent for detergent solution. (b) Optical micrograph of a chip filled with components for mesophase preparation. Lipid: MO (colorless); concentrated detergent solution: 20% βOG in 25 mM NaH2PO4, pH 5.5 (colorless); diluent: 25 mM NaH2PO4, pH 5.5 (red). (c1–c4) Sample formulation protocol. Arrows indicate the direction of fluid movement. (c1) Central chamber of the mixer is filled with lipid (blue). (c2) Auxiliary round dilution chambers are filled with a diluent for detergent solution (red). (c3) Diluent is transferred into side chambers of the mixer by actuating injection valves on top of the round chambers. (c4) Side chambers are filled to volume with concentrated detergent solution (green). Scale bar: 1 mm.