Table I. Comparison of the N’-terminal regions of CYPs that contain chimeric signals for bimodal targeting.

The N-terminal amino acid 1–36 sequence regions were analyzed using ExPaSy (Expert Protein Analysis System) molecular biology server of the Swiss Institute of Bioinformatics. The number of + indicates the degree of α-helicity or hydrophobicity.

Signal parameters	CYP1A1	CYP2B1	CYP2E1
α-Helicity	+ +	+ + +	+
Hydrophobicity	+ + +	+ + + + +	+ +
Stability	Stable	Very stable	Unstable