Table 3. Overlapping IPA Pathways Associated with Expression of Mesenchymal Signature Genes and Genes Up-regulated in IL13Rα2-positive Cell Lines and IL13Rα2 Over-expressing Patient Samples.

IPA-defined Pathway*	Mesenchymal Signature Genes (FDR)	IL13Rα2-positive Cell Lines (FDR)	IL13Rα2 Over-expressing Patient Samples (FDR)
Hepatic Fibrosis / Hepatic Stellate Cell Activation	0.0000054	0.00021	0.0012
TREM1 Signaling	0.000072	0.0036	0.0021
Dendritic Cell Maturation	0.000079	0.049	0.020
Integrin Signaling	0.00096	0.0068	0.014
Agrin Interactions at Neuromuscular Junction	0.0033	0.045	0.031
Caveolar-mediated Endocytosis Signaling	0.016	0.00062	0.012
Type I Diabetes Mellitus Signaling	0.016	0.0091	0.0036
Death Receptor Signaling	0.030	0.0036	0.012
Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis	0.042	0.034	0.019

^*Top overlapping IPA pathways with FDR < 0.05. Immune function-related pathways are indicated in bold.