Figure 2. Comparison between the homology model and crystal structure of CXCR4. (a) Superposition of the full length homology model (yellow) and crystal structure of CXCR4 (Asn35-Leu226 and Arg235-Ser213) (blue) (b) Superposition of the trans-membrane region of the homology model (yellow) and crystal structure of CXCR4 (blue) viewed from extracellular side. (c) Relative position of Tyr45, Trp94, Asp97, Tyr116, Asp171 and Glu288 in the homology model of CXCR4 (grey) on the crystal structure of CXCR4 (orange).
