Table 6. Estimated association coefficients stratified by age tertile, by period, by drinking status, and by smoking status assuming a linear bone-blood association.

	Tibia Lead		Patella Lead
Age Tertile	Estimate	P value	Estimate	P value
1st	0.083	<0.0001	0.068	<0.0001
2nd	0.090	<0.0001	0.069	<0.0001
3rd	0.066	<0.0001	0.049	<0.0001
P-value for age interaction	0.22		0.07
	Tibia Lead		Patella Lead
Period	Estimate	P value	Estimate	P value
Before Jun.13, 1995	0.099	<0.0001	0.074	<0.0001
After Jun.13, 1995	0.060	<0.0001	0.044	<0.0001
P-value for period interaction	<0.001		<0.001
	Tibia Lead		Patella Lead
Drinking status	Estimate	P value	Estimate	P value
Non-drinker	0.094	<0.0001	0.068	<0.0001
Light-drinker	0.072	<0.0001	0.059	<0.0001
Heavier-drinker	0.070	<0.0001	0.053	<0.0001
P-value for drinking status interaction	0.28		0.42
	Tibia Lead		Patella Lead
Smoking status	Estimate	P value	Estimate	P value
Never	0.080	<0.0001	0.060	<0.0001
Ever	0.077	<0.0001	0.061	<0.0001
P-value for smoking status interaction	0.86		0.94

Age tertiles (years): <65.7 (mean 61.1), 65.7-72.2 (mean 68.9), >72.2 (mean 77.3)

Drinking status: non-drinker (0gm/day), light drinker (0-10.97gm/day, mean 4.58), heavier drinker (10.97-37.81gm/day, mean 29.79)

Models adjusted for age, education, alcohol intake, smoking status, and period