Table I.

Demographic clinical and outcome characteristics of the women who provided AF samples for sgp130, sIL-6R and IL-6 levels (n=301).

Variable	2nd trimester genetic amniocenteses n = 39	3rd trimester lung maturity amniocenteses n = 40	Rule-out infection amniocenteses n = 222	P value
Characteristics at amniocentesis
Maternal age, years, †	33 [28 – 38]	30 [26 – 36]	28 [22 – 33]	0.002
Parity †	0 [0 – 1]	1 [0 – 2]	1 [0 – 1]	0.017
Gravidity †	2 [1 – 3]	3 [2 – 4]	2 [1 – 3]	0.162
GA, weeks †	19 [17 – 20]	36 [36 – 37]	29 [25 – 31]	<0.001
Uterine contractions ‡	0 (0)	0 (0)	109 (49)	<0.001
Cervical dilatation > 3 cm ‡	0 (0)	0 (0)	72 (32)	<0.001
PPROM ‡	0 (0)	0 (0)	91 (41)	<0.001
Clinical chorioamnionitis ‡	0 (0)	0 (0)	18 (8)	<0.001
Outcome characteristics
Term delivery (≥ 37 weeks) ‡	39 (100)	23 (58)	31 (14)	<0.001
Preterm birth at < 34 weeks ‡	0 (0)	0 (0)	175 (79)	<0.001
GA at delivery, weeks †	39 [39 – 40]	37 [36 – 37]	31 [27 – 33]	<0.001
Amniocentesis-delivery time, days †	143 [134 – 154]	1 [1 – 4]	3 [0 – 17]	<0.001

^†Data presented as median [interquartile range] and analyzed by Kruskal-Wallis ANOVA on Ranks.

^‡Data presented as n (%) and analyzed by Chi square tests.

Abbreviations: PPROM, preterm premature rupture of membrane; GA, gestational age