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(a) Reaction scheme showing the synthesis and attachment of IDA to the nanoparticle surface. (b) Illustration of the machine assembly process. IDA-modified MCM-41 nanoparticles were loaded with Hoechst 33342, and the nanogate latched through the introduction of CoCl2. The assembled nanogate was washed to remove surface-adsorbed dye and unbound cobalt.
