Table 1.
Default nondimensional parameter values used in simulations of the full model. These values produce a reflecting pulse. Bracketed values produce a wave train. The abbreviation NPF represents the regulatory protein. Values for most dimension-carrying NPF parameters are based on small GTPases in [32], and lead approximately to the above dimensionless values based on scaling discussed in Appendix B.
Parameter | Value | Description |
---|---|---|
DA | 0.00033 | Diffusion coefficient of A |
DI | 0.033 | Diffusion coefficient of I |
k0 | 0.05 (0.2) | Basal rate of activation of NPF |
γ | 1 | Magnitude of NPF positive feedback |
A0 | 0.4 | Level of active NPF for positive feedback to occur |
s1 | 0.5 | Basal NPF inactivation rate |
s2 | 0.6 (1.2) | F-actin-mediated NPF inactivation rate |
kn | 2.0 | Rate of F-actin nucleation by NPF |
ks | 0.25 | F-actin disassembly rate |
ε | 0.1 | F-actin dynamics rate parameter |
TN P F | 1 | Total amount of NPF |