Table 1.
A. Descriptive Statistics of U133A Patient Cohort
Characteristic | N | Caucasian | African American | p-value |
---|---|---|---|---|
#patients | 63 | 52 | 11 | - |
Median age (yrs) | 63 | 63.0 | 60.0 | 0.0582 |
Gleason Score | 63 | 0.3065a | ||
less than 7 | 24 | 3 | ||
equal to 7 | 18 | 7 | ||
greater than 7 | 10 | 1 | ||
Stage: | 61 | 0.7264a | ||
≤pT2 (n) | 35 | 7 | ||
≥pT3 (n) | 15 | 4 | ||
Surgical Margins | 63 | 0.4799a | ||
negative | 35 | 9 | ||
positive | 17 | 2 | ||
PSA | 62 | 9.3 | 8.0 | 0.9120 |
Median tumor volume (cm3) | 54 | 41.2 | 33.8 | 0.6640 |
| ||||
B. Descriptive Statistics of the Tissue Percentages in U133A Array | ||||
Descriptive Stastistics of Total U133A Array
| ||||
Characteristic | N | Caucasian | African American | p-value |
| ||||
#Array files | 99 | 82 | 17 | |
#Tumor Arrays | 58 | 50 | 8 | |
Median tumor % | 43.5 | 41.5 | 0.4913 | |
Median stroma % | 45.5 | 47.0 | 0.7351 | |
#Stroma Arrays | 41 | 32 | 9 | |
Median stroma % | 77.0 | 70.0 | 0.5284 | |
Descriptive Stastistics of Matched U133A Array
| ||||
Characteristic | N | Caucasian | African American | p-value |
| ||||
#Array files | 34 | 17 | 17 | |
#Tumor-matched Arrays | 16 | 8 | 8 | |
tumor%: mean (st.dev) median | 36 (21.4) 41.5 | 35.75 (21.3) 41.5 | 1.0000 | |
stroma%: mean (st.dev) median | 48.25 (18.4) 42.5 | 48.88 (17.8) 47.0 | 0.9162 | |
#Stroma-matched Arrays | 18 | 9 | 9 | |
tumor%: mean (st.dev) median | 0 (0) 0 | 0 (0) 0 | n/a | |
stroma%: mean (st.dev) median | 70.8 (15.2) 70.0 | 71.2 (15.7) 70.0 | 0.8246 |
(1A) Descriptive statistics of the clinical variables in the Affymetrix U133A gene chip data using Wilcoxon Mann Whitney and
Fisher exact test were used to report significant differences between the two groups.
(1B) Descriptive statistics of the cell-type composition in the Affymetrix U133A gene chip data using Wilcoxon Mann Whitney were used to report significant differences between the two groups. There were no significant differences between all arrays or the matched subset.