Table 3.

The Bethesda System for Thyroid Cytopathology

Category	Risk of Malignancy (%)	Recommended Management
Nondiagnostic or Unsatisfactory	1–4	Repeat FNA with U/S guidance
Benign	0–3	Clinical follow-up
Atypia of Undetermined Significance (AUS) or Follicular Lesion of Undetermined Significance (FLUS)	5–15	Repeat FNA*
Follicular Neoplasm or Suspicious for Follicular Neoplasm	15–30	Lobectomy
Suspicious for Malignancy	60–75	Lobectomy +/− frozen section or total thyroidectomy
Malignant	97–99	Total thyroidectomy

FNA, fine needle aspiration

U/S, ultrasound

^*Lobectomy can also be considered depending on clinical or sonographic characteristics