Table 5.

The Effectiveness of UroVysion and Cytology for Bladder Cancer Detection in Patients with History of Low Grade and High Grade Urothelial Cell Carcinoma

	Sensitivity	Specificity	PPV	NPV
Low Grade UCC (n=468)
UroVysion	40.8%	87.8%	4247.1%	84.9%
Cytology
With AUC as −	14.3%†	96.8%†	53.8%	81.0%***
With AUC as +	45.9%	80.2%**	38.1%*	84.9%
High Grade UCC (n=576)
UroVysion	75.65%	84.8%	64.86%	90.4%
Cytology
With AUC as −	37.236.8%†	94.1%†	70.069.5%	80.2%†
With AUC as +	71.2%	78.3%**	55.054.7%**	88.0%

UCC: Urothelial Cell Carcinoma; AUC: Atypical Urothelial Cells; PPV: Positive Predict Value; NPV: Negative Predict Value

^*p<0.05 when compared to the same diagnostic test characteristic for UroVysion;

^**p<0.01;

^***p<0.001;

^†p<0.0001