Table 1. Human papillary dermis nerve staining results.

Human papillary dermal nerve staining	Head/neck/scalp	Trunk	Extremities
% Of PGP9.5(+) nerves that are also GRP(+)1	7.7, 3.8–12.12	7.8, 4.3–10.9	9.8, 7.6–16.62
% Of PGP9.5(+) nerves that are also CGRP(+)1	8.4, 4.6–17.33	20.8, 13.1–30.43a	17.9, 10.3–30.33b
% Of GRP(+) nerves that are also CGRP(+)1	36.3, 6.9–70.24	81.9, 42.6–97.34a	67.2, 35.8–86.64b
% Of CGRP(+) nerves that are also GRP(+)1	20.4, 5.9–44.5	36.6, 22.5–40.1	35.7, 21.3–63.2
% Of PGP9.5(+) nerves that are also SP(+)1	8.8, 4.2–14.7	5.1, 2.2–10.5	8.1, 7.2–15.2
% Of GRP(+) nerves that are also SP(+)1	82.6, 37.3–100	57.7, 0.0–100	100, 74.2–100
% Of SP(+) nerves that are also GRP(+)1	69.3, 46.6–100	42.5, 0.0–89.2	100, 88.3–100
% Of GRP(+) nerves that are also C fibers1	48.1, 20.1–73.6	27.5, 11.3–48.4	12.9, 0–47.8
% Of GRP(+) nerves that are also Aδ fibers1	51.9, 26.4–79.9	72.5, 51.6–88.9	87.1, 52.2–100
% Of GRP(+) C fibers that are also SP(+)1	74.8, 40.6–100	52, 1–100	100, 17.3–100
% Of GRP(+) Aδ fibers that are also SP(+)1	100, 59.3–100	100, 95.2–100	100, 100–100

Abbreviations: CGRP, calcitonin gene–related peptide; GRP, gastrin-releasing peptide; PGP9.5, protein gene product 9.5; SP, substance P.

¹Median, 25–75% quartiles.

²P=0.0184, α=0.05.

^3–3aP=0.005; ^3–3bP=0.0037.

^4–4aP=0.0058; ^4–4bP=0.0294.