Table 1.

Voltage-clamp data

	I (pA): ± 40 mV	I (pA): −10 mV
NT	3430 ± 186 (30)	793 ± 92 (30)
GFP alone	3019 ± 225 (8)	800 ± 116 (9)
GFP control (NT)	3312 ± 456 (8)	763 ± 57 (8)
Kv2.1 DN	2177 ± 173 (30)*	438 ± 35 (30)*
Kv2.1WT	11000 ± 1268 (11)*	2420 ± 435 (11)*
WT control (NT)	2778 ± 270 (11)	847 ± 308 (11)

All measurements were made at 200 ms after the beginning of the voltage step. Holding potential was –78 mV. Data are presented as mean ± SEM (number of cells). Transfected cells were paired with a non-transfected control cell selected in the same layer in the same slice, within ∼50 μm. NT = non-transfected control cells for Kv2.1 DN experiments. Kv2.1 DN = Kv2.1 pore mutant dominant negative construct. GFP control (NT) = non-transfected cells paired with GFP alone cells. Kv2.1 WT = wild-type Kv2.1 (overexpression). WT control (NT) = non-transfected cells paired with Kv2.1 WT overexpression group. *Significant difference from control (P < 0.05).