Figure 1.
The CART-derived decision tree for sepsis diagnosis in patients with a non-lung source of infection, based on IL-27 and PCT. Each node provides the total number of subjects in the node, the IL-27 or PCT serum concentration-based decision rule, and the number of patients with and without sepsis, with the respective rates. Terminal nodes 1, 2, and 4 are considered low sepsis probability nodes, whereas terminal nodes 3, 5, and 6 are considered high sepsis probability nodes. To calculate the diagnostic test characteristics, all subjects in the low probability terminal nodes (n = 116) were classified as predicted no sepsis, whereas all subjects in the high probability terminal nodes (n = 67) were classified as predicted sepsis.