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Pharmacokinetics in mice. hEPO (0.18 mg/kg) and Ab-hEPO (1.5 mg/kg) in PBS (pH 7.4) were administrated by intravenous (i.v.) injection into CD1 mice (three per group). Blood was collected from day 0 to day 14 and analyzed by ELISA using antihuman IgG Fc and anti-hEPO antibodies. Data were normalized by taking maximal concentration at the first time point (30 minutes).
