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. 2013 Jul 30;8(10):2145–2150. doi: 10.1021/cb400430t

Table 2. DDR1-IN-1/2 Anti-proliferation Effect on Cancer Cell Lines.

cell linesa origin DDR1-IN-1 (μM) DDR1-IN-2 (μM)
HCT-116(OWT) colon 8.7 0.81
T47D(OWT) breast >10 1.11
A549(WT) lung >10 2.29
H1975(WT) lung >10 0.89
SaoS2(WT) sarcoma 8.14 0.39
SkBr3(WT) breast >10 3.07
SW480(OWT) colon >10 2.76
SNU-1040(OMT) colorectal >10 3.52
EJ(WT) uterus >10 4.60
SNU-449(OMT) HCC >10 1.10
a

OWT = overexpression of wide type, WT = wide type, OMT = overexpression of mutant type.