Table 2. DDR1-IN-1/2 Anti-proliferation Effect on Cancer Cell Lines.
cell linesa | origin | DDR1-IN-1 (μM) | DDR1-IN-2 (μM) |
---|---|---|---|
HCT-116(OWT) | colon | 8.7 | 0.81 |
T47D(OWT) | breast | >10 | 1.11 |
A549(WT) | lung | >10 | 2.29 |
H1975(WT) | lung | >10 | 0.89 |
SaoS2(WT) | sarcoma | 8.14 | 0.39 |
SkBr3(WT) | breast | >10 | 3.07 |
SW480(OWT) | colon | >10 | 2.76 |
SNU-1040(OMT) | colorectal | >10 | 3.52 |
EJ(WT) | uterus | >10 | 4.60 |
SNU-449(OMT) | HCC | >10 | 1.10 |
OWT = overexpression of wide type, WT = wide type, OMT = overexpression of mutant type.