Table 2.
Complete Model (N=778) | Adjusted Odds Ratio (95% CI) | p-value |
---|---|---|
Initial Serum Lactate Strata | ||
Low | Reference | Reference |
Intermediate | 3.76 (1.06 – 13.31) | 0.04 |
High | 6.42 (1.86 – 22.23) | 0.003 |
APACHE II (baseline) * | 1.06 (1.01 – 1.11) | 0.02 |
Diabetes mellitus | 0.31 (0.13 – 0.77) | 0.01 |
Pulmonary source of sepsis | 3.97 (2.06 – 7.67) | <0.001 |
Microbiologically-proven infection | 2.47 (1.20 – 5.08) | 0.01 |
Shock at presentation | 1.74 (0.87 – 3.49) | 0.12 |
Transfusion at presentation | 1.70 (0.69 – 4.21) | 0.25 |
Definition of abbreviation: APACHE=Acute physiology and chronic health evaluation score; CI=confidence interval.
An adjusted odds ratio of greater than 1 indicates that the factor is associated with greater odds of developing ARDS. The following variables did not alter the odds ratio estimates of the candidate risk factors significantly, nor were they significantly associated with ARDS development: serum creatinine, platelet count, chronic renal insufficiency, human immunodeficiency virus, urosepsis, soft-tissue infection, or admission type (medical vs. surgical).
Odds ratio for each 1-unit increase in baseline APACHE II score.