Fig. 2.

Light microscopy of cross sections of H&E stained testis from ZNP treated mice. a ZNP-1 (5 mg/kg ZNP) group: vacuoles (V) and detachment (D) are observed in some tubules. b ZNP-2 (50 mg/kg ZNP) group: histopathological changes including detachment and vacuolization are observed. c ZNP-3 (300 mg/kg ZNP) group: disorganization of germ cell layers includind sloughing (S), detachment and vacuolization are markedly increased. d multinucleated giant cells (M) in the seminiferous tubules are observed in ZNP-3 group. (a, b and c: ×250; d: ×400)