Figure 5.

Effects of FXT on the expression of occludin and ICAM-1 of retina in STZ rats. Diabetic rats received a single dose of 60 mg/kkg STZ by i.p. Control rats received vehicle. After one week, STZ rats with blood glucose levels greater than 16.7 mmol/L were assigned into STZ group, FXT 0.525 g/kg group, and FXT 1.05 g/kg group. FXT-diabetic rats received FXT 0.525 g/kg or FXT 1.05 g/kg by ig once daily for consecutively 24 weeks. Occludin and ICAM-1 in retina were detected with western blot. The expression of occludin (a) and ICAM-1 (b) was quantified using densitometry and normalized by β-actin. Values are demonstrated as mean ± SD; n = 8; *P < 0.05 versus control rats; ^# P < 0.05 versus STZ rats.