Table 2.
Incidence of toxicities in treated patients.
| Toxicities | Normal no. (%) | G1,2 no. (%) | G3 no. (%) | G4 no. (%) |
|---|---|---|---|---|
| Haematological toxicity | ||||
| Neutropenia | 34 (58.6) | 16 (27.6) | 8 (13.8) | — |
| Febrile neutropenia | 40 (69) | 15 (25.9) | 2 (3.4) | 1 (1.7) |
| Anemia | 20 (34.5) | 34 (58.6) | 4 (6.9) | — |
| Thrombocytopenia | 50 (86.2) | 8 (13.8) | — | — |
| Nonhaematological toxicity | ||||
| Skin and nail disorders | 4 (6.9) | 26 (44.8) | 11 (19) | 17 (29.3) |
| Scaling | 16 (27.6) | 25 (43.1) | 9 (15.5) | 8 (13.8) |
| Stomatitis | 30 (51.7) | 20 (34.5) | 6 (10.3) | 2 (3.4) |
| Hand-foot syndrom | 23 (39.7) | 15 (25.9) | 6 (10.3) | 14 (24.1) |
| Erythema | 48 (82.8) | 10 (17.2) | — | — |
| Paresis | 27 (46.6) | 17 (29.3) | 10 (17.2) | 4 (6.9) |
| Paresthesia | 20 (34.4) | 16 (27.6) | 19 (32.8) | 3 (5.2) |
| Myalgia | 41 (70.7) | 11 (19) | 4 (6.9) | 2 (3.4) |
| Arthralgia | 23 (39.7) | 19 (32.8) | 13 (22.4) | 3 (5.1) |
| Nausea | 6 (10.3) | 36 (62.1) | 10 (17.2) | 6 (10.3) |
| Vomiting | 21 (36.2) | 25 (43.1) | 7 (12.1) | 5 (8.6) |
| Fluid retention | 38 (65.5) | 18 (31.1) | 2 (3.4) | — |
| Phlebitis | 51 (87.9) | 4 (6.9) | 3 (5.2) | — |
| Any grade 4 event | 32 (55%) | |||
| Death | 2 (3.4) | |||