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Matrix effects and extraction recovery of aesculin and the internal standard in rat plasma.
| Analytes | Concentration (ng/mL) | Matrix effects (%, n = 6) |
CV (%) | Extraction recovery (%, n = 5) |
CV (%) |
|---|---|---|---|---|---|
| Aesculin | 40.0 | 98.1 ± 5.6 | 5.7 | 97.6 ± 7.4 | 7.6 |
| 500.0 | 106.4 ± 3.8 | 3.6 | 95.8 ± 6.6 | 6.9 | |
| 1200.0 | 94.2 ± 6.9 | 7.3 | 105.3 ± 4.1 | 3.9 | |
|
| |||||
| IS | 10.0 | 96.2 ± 3.3 | 3.4 | 97.5 ± 5.8 | 5.9 |
| 10.0 | 100.6 ± 5.2 | 5.2 | 104.7 ± 4.8 | 4.6 | |
| 10.0 | 104.2 ± 4.1 | 3.9 | 98.2 ± 3.9 | 4.0 | |
