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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: Mol Imaging Biol. 2013 Dec;15(6):10.1007/s11307-013-0653-8. doi: 10.1007/s11307-013-0653-8

Figure 3.

Figure 3

In vitro specificity and internalization of radiolabeled EMD72000 mAb F(ab’)2 conjugates. (a) Cell binding assay showing specificity of radiolabeled EMD72000 mAb F(ab’)2 conjugates for U87ΔEGFR. Control samples contained a 10-fold molar excess of unlabeled conjugates. (b) U87ΔEGFR cell-surface binding (black bars) and internalization (white bars) of the conjugate mixture at the optimized HRP/GOX ratio (1:2, w/w) in U87ΔEGFR (Δ) and U87-MG (WT) cells at 4°C and 37°C.