Figure 2.

A 75-year-old asymptomatic woman underwent breast ultrasonography and digital mammography. (A) Screening breast ultrasonography shows an indistinct hypoechoic nodule in the right upper inner periareolar portion. Thus, we recommended diagnostic mammography after marking the lesion with a round metal marker. (B, C, D) Right mediolateral oblique and craniocaudal views (B and C) show a spiculated, isodense nodule (arrow) unmarked by computer-aided detection (CAD); however, CAD marked another lesion (D-asterisk, '*') in the upper portion and benign vascular calcifications (D-triangle, '▲') in the outer portion. The lesion was confirmed to be an invasive lobular carcinoma.