The course of disease of EHEC O157:H7 infection differs from that of STEC
O104:H4. Note the longer median incubation time before symptom onset for the
STEC O104:H4 outbreak strain compared with EHEC O157:H7. (Data
from Tarr PI, Gordon CA, Chandler WL. Shiga-toxin-producing
Escherichia coli and haemolytic uraemic syndrome. Lancet
2005;365(9464):1073–86; and Frank C, Werber D, Cramer JP, et al. Epidemic
profile of Shiga-toxin-producing Escherichia coli O104:H4
outbreak in Germany. N Engl J Med 2011;365(19):1771–80.)