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l-Arginine Improves Glucose Tolerance in Mice. A, Blood glucose following oral l-arginine (1 g/kg) or saline to lean C57bl/6 mice 15 minutes before an OGTT (2 g glucose/kg · bw) (2-way repeated measures ANOVA, n = 7). B, Glucose area under the curve (AUC) (t test). C, Plasma GLP-1 (total) levels before and 15 minutes following oral gavage of l-arginine (1 g/kg) (paired t test, n = 17). Data presented as mean ± SEM. *, P < .05; ***, P < .001.
