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The GLP-1R Is Necessary for l-Arginine-Induced Improvements in Glucose Tolerance. Blood glucose following oral gavage of l-arginine (1 g/kg) or saline to lean WT (A) and Glp1r KO (B) mice 15 minutes before an OGTT (2 g glucose/kg · bw) (2-way repeated measures ANOVA, n = 8–9). C, Glucose area under the curve (AUC) (2-way repeated measures ANOVA, n = 8–9). Data presented as mean ± SEM. **, P < .01; ***, P < .001.
