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. 2013 Oct 21;7:149. doi: 10.3389/fnbeh.2013.00149

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Copyright © 2013 Klug and van den Buuse.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Percentage prepulse inhibition (PPI) expressed per prepulse intensity in the four treatment groups: WT/veh, WT/CP, HET/veh, and HET/CP in both sexes. All groups were administered saline (Sal; open bars) or 0.4 mg/kg CP55,940 (CP; black bars) PP2, PP4, PP8, and PP16 indicate prepulse intensities of 2, 4, 8, and 16 dB over the 70 dB background with a 100 ms interstimulus interval. Data are mean ± SEM. ^*P < 0.05 for difference with acute saline treatment based on ANOVA main effect (PP8 and PP16) or CP × genotype × pre-treatment interaction and pair-wise comparison (PP2).