Table 3.
Adjudicated causes of death among non-diabetic and diabetic patients
| Non-diabetics |
Diabetics |
|||
|---|---|---|---|---|
| Adjudicated cause of death, n (%) | Aliskiren (n = 489) | Placebo (n = 465) | Aliskiren (n = 319) | Placebo (n = 345) |
| CV death | 67 (13.7) | 88 (18.9) | 67 (21.0) | 56 (16.2) |
| Fatal myocardial infarction | 3 (0.6) | 6 (1.3) | 1 (0.3) | 6 (1.7) |
| Pump failure | 23 (4.7) | 33 (7.1) | 31 (9.7) | 23 (6.7) |
| Sudden death | 28 (5.7) | 30 (6.5) | 18 (5.6) | 15 (4.3) |
| Presumed sudden death | 3 (0.6) | 1 (0.2) | 4 (1.3) | 2 (0.6) |
| Presumed CV death | 4 (0.8) | 10 (2.2) | 7 (2.2) | 4 (1.2) |
| Other CV death | 0 | 0 | 0 | 2 (0.6) |
| Fatal stroke | 3 (0.6) | 5 (1.1) | 3 (0.9) | 2 (0.6) |
| CV procedural | 1 (0.2) | 0 | 0 | 1 (0.3) |
| Unknown | 2 (0.4) | 3 (0.7) | 3 (0.9) | 1 (0.3) |
| Non-CV death | 8 (1.6) | 5 (1.1) | 10 (3.1) | 4 (1.2) |
| Accidental | 1 (0.2) | 0 | 3 (0.9) | 0 |
| Pulmonary | 0 | 0 | 1 (0.3) | 0 |
| Infection | 3 (0.6) | 1 (0.2) | 6 (1.9) | 2 (0.6) |
| Malignancy | 2 (0.4) | 1 (0.2) | 0 | 0 |
| Gastrointestinal | 1 (0.2) | 3 (0.7) | 0 | 2 (0.6) |
| Renal | 0 | 0 | 0 | 0 |
| Other non-CV death | 1 (0.2) | 0 | 0 | 0 |
CV, cardiovascular.