Fig. 3.

Fucosylation determines transcriptional responses of B. thetaiotaomicron in the intestines of monocolonized Fut2⁻ and Fut2⁺ mice fed a PD diet. Heat map showing significantly regulated genes within 11 PULs (associated with SusC/SusD-like gene pairs) and the fucose catabolic operon (n = 4 mice per genotype). All genes shown exhibit significant differences between the two host genotypes with the exception of BT0438 and BT3856. Colors indicate the deviation of a gene’s signal above (red) and below (green) its mean expression value across all eight samples.