Table 1.

α-Values for urea and GuHCl (Eq. 1) and ε-values (Eq. 2) for the composition of the amide and hydrocarbon surfaces buried in protein folding (SI Materials)

Property	Amide	Hydrocarbon
GuHCl α-value, cal⋅mol−1⋅m−1⋅Å−2	−2.2 ± 0.2	0.11 ± 0.05
Urea α-value, cal⋅mol−1⋅m−1⋅Å−2	−0.42 ± 0.01	−0.11 ± 0.03
ΔCp ε-value, cal⋅mol−1⋅K−1⋅Å−2	−0.14 ± 0.04	0.34 ± 0.02